On Tuesday, May 6, 2025, Inter Milan and Barcelona will clash in the second leg of their UEFA Champions League semifinal at San Siro. Following a thrilling 3-3 draw in the first leg, both teams are eager to secure a spot in the final. The match promises high stakes and intense action, with fans and bettors alike anticipating a captivating encounter.
Inter Milan vs Barcelona Match Preview
The first leg at the Estadi Olímpic Lluís Companys was a rollercoaster. Inter Milan stunned the hosts with an early goal from Marcus Thuram and a spectacular overhead kick by Denzel Dumfries, establishing a 2-0 lead within 21 minutes. Barcelona responded with vigor; 17-year-old Lamine Yamal scored a brilliant solo goal, and Ferran Torres equalized before halftime. Dumfries added another for Inter, but a deflected shot from Raphinha leveled the score at 3-3. Both teams had opportunities to win, but the match ended in a draw, leaving the tie finely balanced.
Heading into the second leg, both sides face injury challenges. Key players like Robert Lewandowski of Barcelona and Benjamin Pavard of Inter are set to miss this huge match. Despite these setbacks, Inter’s recent form at home has been solid, with a strong defensive record, and they will look to advance to the final. However, their defense showed vulnerabilities in the first leg, which Barcelona will aim to exploit.
Barcelona, under the guidance of Hansi Flick, has shown resilience and attacking prowess. Lamine Yamal’s emergence as a dynamic forward adds a new dimension to their offense. Despite defensive struggles in the first leg, Barcelona’s attacking options remain potent and they could overcome their shortcomings to face the winner of PSG vs Arsenal in the final.
Betting Insights
As the match approaches, betting markets reflect the closely contested nature of the tie. Current odds from DraftKings Sportsbook are as follows:
- Inter Milan to win: +195
- Barcelona to win: +115
- Draw: +290
Given the attacking talents on both sides and the high-scoring first leg, the over/under for total goals is set at 3.5, with odds favoring the under at -130. Both teams to score is also a popular bet, priced at -280, reflecting expectations of another open and offensive match.
Inter Milan vs Barcelona Prediction

Draw (+290)
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- The first leg of this tie was a draw and we should see another evenly-matched game here.
- Both teams are so gifted on the attack that neither can be counted out at any point.
Considering the first leg’s dynamics and current team conditions, the second leg is poised to be another high-scoring affair. Inter Milan will leverage their home advantage and aim to capitalize on set-pieces and counter-attacks. Barcelona, with their attacking depth and momentum, will seek to control possession and create scoring opportunities.
Given the attacking capabilities and defensive vulnerabilities on both sides, a draw in regulation time appears likely, potentially leading to extra time or penalties. Bettors might consider wagering on both teams to score and the over 2.5 goals market.
Prediction: Inter Milan 2-2 Barcelona (Barcelona advances on penalties)